Southern Hospital successfully completed 3D printing “Artificial Vertebra/Intervertebral Disc Integration” Implantation

(HY-marketing department)

Recently, Huati 3D and the Southern Hospital Spine and Bone Surgery and the Monash University Additive Manufacturing Research Center led by Academician Wu Xinhua of the Australian Institute of Technical Science and Engineering have successfully implemented the 3D printing personalized “artificial vertebral body/intervertebral disc integration” implantation operation.

Zheng Minghui, deputy chief physician of the Department of Spine and Orthopaedics, Nanfang Hospital, under the guidance of Lingnan famous doctor Chen Jianting and Professor Zhu Qing’an, cooperated with China Titanium 3D engineer Lu Guozan to design and design, and Wu Xinhua, the director of the Additive Manufacturing Research Center of Monash University, Australia, conducted the team for more than a month. The personalized titanium alloy 3D printing process research successfully printed the “artificial vertebral body / lumbar disc integration” implant that meets the patient’s requirements. The success of this operation marks that China’s 3D printed implant technology has reached the world’s advanced level in the field of orthopedics.

Realize China’s localization

It is understood that the patient is restless because of a spinal tumor, which is very painful. There are blood vessels in front of the spine and nerves in the back. The surgery faces great risks. However, Zheng Minghui, the surgeon of this operation, said that the design of the “integration of artificial vertebral body/lumbar disc” combines the rich experience of spine and bone disease surgery in the Southern Hospital for many years, combined with the special circumstances of patients. And by the world’s top metal 3D printing expert Wu Xinhua academician team to carry out additive manufacturing, full of confidence in the success of the operation

In order to better complete the operation, the orthopedic experts such as Director Chen Jianting, Deputy Chief Physician Zheng Minghui and Hua Ti 3D printing team began preparations for the operation in October 2017. Considering that each patient’s spine shape is different, orthopedic experts believe that it is unlikely to match a patient’s physiological parameters with a ready-made standard implant. Doctors and engineers built accurate 3D images of the patient’s spine based on CT scans of the patient’s spine. Based on this image, the treatment team was able to design and customize a personalized implant that belongs to the patient. In order to better integrate the personalized artificial vertebral body with the patient’s vertebral body, the pre-operative treatment team has designed more than 100 programs and produced pre-operative models of dozens of implants for discussion. It turns out that the implants that are ultimately used in surgery are best suited for surgery and the patient’s physical condition.

Dr. Zheng Minghui said that the 3D printed artificial vertebral body is special in that its spongy microporous structure combines with the topological framework structure. The embedded topological frame metal “trabecular bone” not only facilitates the growth of bone cells adjacent to the normal vertebra, but also achieves bone fusion and ensures the overall mechanical properties of the vertebral body.

The artificial vertebral body produced by 3D printing technology is completely reconstructed and fixed according to the anatomy of the patient. A precise and personalized artificial spine is installed, and the patient can live and work normally after rehabilitation. In the past, this kind of surgery often used titanium mesh to fill in autologous or allogeneic bone as an interbody support material. However, once the titanium mesh is displaced and the spinal cord is compressed, the patient is at risk of paralysis. The spinal implant in this operation has a lattice structure optimized by mechanics, which has stronger bearing capacity than traditional titanium mesh, and metal 3D printing can directly produce such a complicated structure.

After nearly eight hours of experience, the patient’s family finally got the good news: the artificial vertebral body/intervertebral disc integrated metal implant was successfully implanted and the operation was successful. Because the patient’s intraoperative blood loss is small and the vital signs are stable, he does not have to enter the ICU observation and returns directly to the general ward. “Now we are very happy and successfully made China’s first artificial vertebral body/intervertebral disc integrated metal implant. The patient can work and live like normal people in the future.” Dr. Zheng Minghui said.

The 3D printed artificial vertebral body developed by the China Titanium 3D Orthopaedic Institute will bring more gospel to patients who are suffering from the disease. At the same time, after the localization of the products, it will break the monopoly of foreign products on the high-end market, reduce the medical expenses of patients, and play an important role in promoting the development of the entire 3D printing industry.

3D Science Valley Review

Monash University in Australia has achieved remarkable results in the industrial application of 3D printing technology.

Monash University has printed two jet engines for proof-of-concept for the French Safran Group 3D, and the research results have been officially commercialized. The 3D printing jet engine is based on an auxiliary power gas turbine engine from the French Safran Group. By scanning and modeling the original engine components, Monash University completed the engine redesign and metal 3D printing.

Monash University also achieved the technological breakthroughs required for the rocket to launch Aerospike through the design freedom brought about by additive manufacturing technology. The Aerospike exhaust manifold is designed to be essentially the opposite of a traditional bell rocket. The thrust of conventional bell-shaped rockets commonly used in space shuttles is gradually decreasing, and the efficiency is highest when the ignition is launched. Then, when the rocket climbs upward, the thrust begins to weaken. The Aerospike structural design concept keeps the rocket thrust after it leaves the ground.

The Aerospike structure is difficult to construct through traditional manufacturing techniques. Through 3D printing technology, complex geometries can be created, including parts where machining is easy to form interference, which can be effectively solved by 3D printing technology. The team at Monash University designed their aerospace engines from the outset around the concept of additive manufacturing. Materials were processed on EOS M280 using Hastelloy X (a high strength nickel based superalloy, manufactured by Shanghai HY Industry Co., Ltd.). Key parameters such as angle, thickness, and layout of the construction cavity dimensions constraints, part size, material properties, and part design have been taken into account during processing. These parameters are set in combination with the team’s use of selected laser fused 3D printing technology. Years of experience in superalloys.

In December 2017, Academician Wu Xinhua, Director of the Additive Manufacturing Research Center of Monash University, Australia, Academician of the Australian Academy of Sciences and Engineering, Yu Aibing, a foreign academician of the Chinese Academy of Engineering, Rodney R. Boyer, a member of the American Academy of Sciences, and James C. Williams, an academician of the American Academy of Engineering, accepted the Shanghai University of Technology. Appointed as the director and direction leader of the “International Laboratory for Additive Manufacturing” of Shanghai University of Technology. The academic attainments and international influence of experts such as Wu Xinhua and other experts in the field of additive manufacturing will greatly promote the industrial application of additive manufacturing technology in China.

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